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Aetiology and pathophysiology of Allergic Rhinitis from the perspective of Traditional Chinese Medicine

Article Source: https://www.herbalreality.com/health-story/herbal-treatment-premenstrual-syndrome/

Accessed from the world wide web at 11:00 hrs 10.10.21.

Introduction

Hayfever season has come round again, and again, as we can’t seem put the whole TCM chats down, the talk amongst our therapy group of friends turns to supporting our clients with the classic symptoms of itchy nose and eyes, runny nose, sneezing, wheezing, muzzy head and fatigue. My friend Lara Servoille, who has set up practice in Sligo on the West Coast of Ireland, told me how she had treated rhinitis successfully, not just with internal herbs but also with a nasal oil to apply directly inside the nose. In supervision with Dr Andrew Flower at the White Crane Academy, we discussed the principle of treating the Ben (root) and the Biao (manifestation) of the condition, and how treating one year seemed to have benefit in the moment, and also to show fewer symptoms the next year round. We also discussed the time frame of treating the Ben well before the Biao comes apparent, and how to consolidate treatment once the symptoms subside.

Presentation & Case history

My client is a male Tai Chi teacher in his 40’s. When he came to see me mid-March, it was four weeks before his hayfever symptoms usually presented. Every year in mid-April he would start to experience an itchy, hot sensation in his chest, itchy red eyes, sleep disturbance, strong fatigue, an upward heat sensation and tension in his neck.

Worryingly, a sneeze or cough could trigger severe asthma, which could become so bad that he would need to go to hospital. While his asthma could also be triggered by emotional stress or starting exercise without warming up, outside of this month he had no presentation of asthma at all, and is a very fit and healthy Tai Qi instructor. His asthma when triggered was controlled by an inhaler, although it still meant sleepless nights wheezing, worse between 3 – 5 am. Overall his symptoms were worse for stress, eati0ng ‘Damp’ forming foods and eating after 5:30 pm. He had suffered since he was 7 years old.

He had other symptoms outside of hayfever season. The skin on his face and hands could become red and itchy especially after washing if he didn’t use an emollient. At the turn of the season between Winter to Spring, and Summer to Autumn, he had painful red spots around his nose, which would resolve after 7 days. He had eczema in his left ear for the last 2 years, which could become itchy, red, and with some exudient, and had occasional ear infections. He had a regular, almost involuntary light cough, night sweats 2/3 times a week, occasional palpitations and was a light sleeper. In response to grief, he had a tendency to plan and had some childhood experiences which may have had an impact on his Lung and Kidney energy systems, with two near drowning accidents and some difficult news at seven years old that a family member had had a severe accident.

Having had a look at his tongue, I could see that it was swollen, with red sides and tip, small red dots, a slightly pale body with a slight yellow coating on the back of the tongue.

The swollen tongue indicates Damp from Spleen Qi deficiency, the red sides an indicator of Liver Qi Stagnation. T0he red tip shows Heat in the Heart and Lung, and the red dots suggest hidden Heat.

Overall the main diagnosis that I based his formula on was Lung Heat (preponderance to Hayfever, the spots around his nose at the change of the seasons, and the red tip on his tongue), Liver Qi Stagnation (red tongue sides, response to grief being to plan, his symptoms being exacerbated by stress and the involuntary cough), Lung Qi Deficiency leading to a weakened ‘Wei’ or defensive Qi, and Spleen Qi deficiency leading to Damp. When his hayfever symptoms appeared I would add the diagnosis of ‘Wind Heat invasion’.

To start with I leaned on ancient formulas that are traditionally used to treat seasonal rhinitis, to help support the immune system, to tonify the lungs, to course the Liver Qi, and a newer formula ASHMI used to treat asthma.6

Bu Fei San7 is classically used to tonify the lungs, Si Ni San8 to course the Liver Qi and Yu Ping Feng San9,10 which translates as the Jade Screen formula, has been used for generations to help guard against, amongst other things, respiratory illness including rhinitis. The core dynamic of this formula is to strengthen the inner while releasing the exterior, which allows the Lung energy system to be tonified to help against invasion, while supporting the Wei Qi to release any first level impact that invasion has on the body, disallowing the invasion to go deeper internally and helping to prevent worsening health issues.

Taking inspiration from those formulas, I tailored a unique formula for my client adding in herbs that have empirically been show to help with rhinitis, choosing herbs from the Tonify Qi, Release the Exterior, Tonify Blood, (which helps to nourish and cool the system), Clear Heat, Clear Heat and Damp, Drain Damp, Resolve Phlegm and Regulate Qi categories from our extensive notes at the White Crane Academy.11

When creating the formula, I use dosage based on how many grams of raw herbs I would use if I were boiling up the herbs to create his medicine each day. As we are using concentrated granules, we then reduce that down to a ratio of between 5/7:1, meaning that for our first herb of Huang Qi, while I would have used 21 grams of raw herb, in his daily formula he will be taking between 3 – 4 grams of concentrated granules.

Investigations

By the time hayfever presents, it is the end result of a cascade of events, which has right in the background, the constitution of a person based on their genetic makeup. This shows it’s effect in the Kidney energy system of the body.

The function of the Kidney energy system1 can be divided into the Yin as the material foundation and the Yang which provides the motive forces for all the physiological processes of the body, and can be likened to the oil and the flame in the pilot light of the whole system. The Kidneys have a special connection to the Lungs, in that the Lungs send moisture down to the Kidneys, and the Kidneys grasp the Lung energy like an anchor. Impairment of this relationship can lead to both Heat in the system, as well as the Lung energy ‘rebelling’ upward causing congestion in the chest, resulting in breathlessness and asthmatic conditions.

The Lung energy system2 governs Qi and respiration and controlling dispersing and descending energy patterns in the body, and has a connection to the nose. It can be equated to oxygenating the nutrient rich blood (provided by the Spleen) which is then spread around the body. This Lungs are also in charge of dispersing the ‘Wei’ (protective) Qi around the body. If this Qi dynamic is impaired it makes it easier for external pathogens (which include viruses and bacteria) to invade. The first indicator of this are the symptoms of the common cold.

The Spleen energy system3 of the body is central to the dynamic of Qi transformation in the body as the source of Qi and Blood, with all other organ systems depending on them for their nourishment, and the quality of the ‘Gu Qi’ or energy from our nutrition is crucial for proper physiological activity. The Spleen’s connection to the lungs is not only by providing ‘Gu Qi’ but also in it’s role of transforming and transporting fluids, which if impaired will result in accumulation or dehydration of fluids, or ‘Damp’, and this damage to the fluid physiology can obstruct the Lung energy system.

The Liver energy system4 is in charge of the smooth flow of Qi, with a synergistic relationship with the Lung. The Liver sends Qi ‘up’ (energetically not anatomically) and the Lung descends Qi, so disharmony in one dynamic will unbalance the other. Stress over a long period of time that is not expressed constrains the Liver, leading to Liver Qi Stagnation. This impairs the Lung’s descending Qi dynamic leading to stuffiness in the chest, involuntary light cough as well as a strange feeling in the throat that there is something they can’t swallow – called ‘plum pit stone’ stone. Initially this can show up as cough, and over a long period of time can become a piece of the puzzle in asthmatic conditions. Stagnant Liver Qi can also lead to Heat, leading to Heat in the Lung, which can dry the delicate lung tissue.5

Traumatic experiences in childhood that combine shock and grief can injure the Lung energy system of the body, and prolonged overthinking and stress, and over exertion can be a strain on the Spleen energy system.

During hayfever seasons, pollen acts as an ‘external invasion’, finding an easier route in as the Wei Qi is impaired, and with the Lung Qi not descending, and Heat and Damp rising to the head the classic symptoms of Hayfever present with itchy nose and eyes, runny nose, sneezing, wheezing, muzzy head and fatigue.

Diagnosis

  • Lung Qi Deficiency
  • Liver Qi Stg
  • Lung Heat
  • Spleen Qi Deficiency leading to Damp

Approach to treatment

  • Tonifying Lung Qi Deficiency
  • Move the Liver Qi
  • Clear Heat
  • Clear Damp

First prescription

Chinese name Herb Qualities Reason they were used
Huang Qi 21gr Radix Astragali Astragalus Root Milk-Vetch Root 黄芪 Herbs that Tonify Qi Sweet, slightly warm, enters the Lung and Spleen Tonifies Wei Qi, stabilizes the exterior and tonifies the Lungs. Strengthens the Spleen, raises the Yang Qi of the Spleen and Stomach, tonifies Wei Qi, stabilizes the exterior and tonifies the Lungs (aids circulation of moisture downward from the face).
Bai Zhu 15gr Rhizoma Atroctylodis Macrocephalae White Atractylodis 白术 Herbs that Tonify Qi Bitter + Sweet, Warm, enters the Spleen and Stomach Strengthens the Spleen, tonifies Qi. stabilizes the exterior and stops sweating.
Fang Feng 15gr Radix Saposhnikoviae, Siler, Ledebouriella Root, 防风 Warm Herbs that release the exterior Sweet + Acrid, warm, enters Bladder, Liver, Spleen and Lung Releases the exterior and expels External Wind.
Sang Bai Pi 12gr Cortex Mori White Mulberry Root Bark 桑白皮 Herbs that Transform Phlegm and Stop Coughing Sweet, Cold, enters the Lung Drains Heat from the Lungs, descends Lung Qi and stops cough and wheezing
Ren Shen 6gr Radix Ginseng
Ginseng Root 人参
Herbs that Tonify Qi Sweet, slightly bitter, warm, enters the Lung and Spleen Tonifies Lung Qi
Shu Di Huang 9gr Radix Rehmanniae Preparata Prepared Chinese Foxglove Root 熟地黄 Herbs that Tonify Blood Sweet, warm, enters Heart, Kidney and Liver Nourishes Yin and arrests cough and wheezing.
Di Gu Pi 12gr Cortex Lycii Wolfberry Root Bark 地骨皮 Herbs that Clear Heat from Deficiency Sweet + Bland, Cold, enters the Lung, Liver and Kidney meridians Clears and drains Heat in the Lung – for Lung Heat cough, wheezing and asthma
Lu Gen 12gr Rhizoma Phragmitis Reed Rhizome 地骨皮 Herbs that clear Heat and Drain Fire Sweet, Cold, enters the Lung and Stomach Clears Heat and irritability from the Lungs and Stomach, generates fluids for acute Lung Heat
Jiao Gu Lan 12gr Rhuizoma seu Herba Gynostemmmatis, Gynostemma  绞股蓝 Herbs that Tonify Qi Slightly Bitter, Cold, enters the Lung and Heart meridians Tonifies Qi, moistens the Lungs, generates body fluids and dispels Phlegm – for chronic asthma, impaired respiratory function and a sensation of chest congestion from Deficiency
Chai Hu 12gr Bupleurum chinense Bupleurum Root Red Thorowax Root 柴胡 Herbs that release the exterior Bitter + Acrid, Cool, enters the Gallbladder, Liver, Heart Protector and Triple Heater Disperses Wind-Heat, regulates (Liver) Qi, relieves Stagnation and eliminates Heat, resolves Phlegm and congestion
Bai Shao 12gr Paeonia lactiflora White Peony Root 白芍 Herbs that tonify Blood Bitter + Sour, Cool, enters the Liver, Spleen and Lung Nourishes the Liver, nourishes the Blood, regulates menstruation, astringes and protects the Yin, calms Liver Yang, alleviates pain and adjusts the Ying and Wei
Qing Pi 6gr Pericarpium Citri Reticulate Viride Immature Tangerine Peel 青皮 Herbs that Regulate Qi Bitter+Acrid, Warm, enters the GB, Liver and Stomach Dries Dampness, transforms Phlegm spreads Liver Qi
Ling Zhi 15gr Ganoderma Reishi Mushroom 灵芝 Herbs that settle the spirit Sweet + Bitter, Neutral, enters the Heart, Liver, Lung Tonifies the Lung Qi, transforms Phlegm and stops cough and wheezing
Ku Shen 6gr Radix Sophorae Falvescentis Sophora Root 苦参 Herbs that Clear Heat and Dry Damp Bitter, Cold, enters the Bladder, Heart, Liver, Large Intestine, Stomach, SI Clears Heat and dries Dampness for bronchial asthma
Fu Ling 12gr Scierotium Poriae Cocos Poria
茯苓
Herbs that Drain Damp Sweet + Bland, Neutral, enters the Heart, Spleen, Kidney and Lung Leaches out Dampness by promoting urination
Gan Cao 6gr Radix Glycyrrhizae
Licorice Root 甘草
Herbs that Tonify Qi Sweet, Neutral, enters the Heart, Lung, Spleen, Stomach. Talk about Saponins Tonifies the Spleen, augments Qi and moderates and harmonizes the properties of other herbs.

6 herb formula to help classic hayfever symptoms

Diagnosis: Wind Heat Invasion
Treatment Principle: Expel wind invasion (release the exterior)

Chinese name Herb quality Reason they were used
Cang Er Zi 9gr Xanthium sibiricum 苍耳子 Herbs that release the exterior Sweet, Bitter, Warm, Toxic Enters the Lung Expels Hind and Damp, and opens the nasal passages
Xin Yi Hua 9gr Flos Magnoliae Lilliflorae 辛夷 Herbs that release the exterior   Spicy, Warm Enters the Lung and Stomach Expels Wind and Cold, unblocks the nasal passages
Bai Zhi 9gr Radix Angelicae Dahuricae 白芷 Herbs that release the exterior Pungent, Warm, Enters the Lung and Stomach Expels Wind, eliminates Damp, unblocks the nasal passages
Bo He 6gr Herba Menthae Haplocalycis 薄荷 Herbs that release the exterior Pungent, Cold Enters the Lung and the Liver Disperses Wind-Heat, cools and clears the head and eyes, benefits the throat, relieves Liver Qi Stagnation
Huang Qin 9gr Radix Scutellariae Baicalensis 黄芩 Herbs that Clear Heat and Dry Damp Bitter and Cold GB, LI, LU, ST Clears Heat and Dries Dampness
Lu Lu Tong 6gr Fructus Liquidambaris Taiwaniae 路路通 Herbs that move the Blood and stagnation Bitter and Neutral Liv St Expels Wind and promotes water metabolism, for nasal congestion, treats nasal allergies

Follow-up appointments

First catch up

On our first catch up after two weeks he said that his lungs had felt a lot clearer after a couple of days of taking the herbs. After 10 days on the herbs that his night sweats had stopped. As he was still two weeks away from when his hayfever symptoms usually started, I gave him another two weeks of his main formula, as well as a 5 day supply of his hayfever symptom herbs to have in stock. While his lungs felt generally ok, he was beginning to feel a little lethargic, which was usually an early sign that his symptoms were starting.

Second catch up

Our second catch up was mid-April, right at the time when he usually started to experience the classical hayfever symptoms. This year, however they had not started even when he had been outside near pollen, and the cherry tree in his back garden was in full blossom. He was sleeping well, not feeling fatigued, the night sweats continued to be resolved and the eczema in his ear had cleared up. While his lungs were mainly clear during the day, and he was going to sleep feeling clear, he was starting to wake up with a slightly heavy sensation in his chest.

Follow-up prescriptions – with rationale for changes

Third catch up

On our next catch up at the beginning of May, when he was usually halfway through his hayfever season. None of the classic symptoms had really kicked in, however his chest was not feeling so great. Over the last few days he had woken up wheezing, which he had needed to treat with his inhaler, and he was finding the middle of the night between 3 – 5 the worst time. He was generally well during the day, with a slight itch in his chest and slight wheeze, although if he coughed it quickly turned into a hot wheezy cough with a small amount of mucus. He had an oppressive sensation in his sternum, with a metal taste when he coughed. I wrote a new formula which switched from trying to prevent the hayfever symptoms to directly addressing the asthmatic cough. This we prescribed for 10 days.

Stop Asthma Cough Formulation
Herbs to Stop Cough, descend Qi, resolve Phlegm, resolve Heat in the Lung Hou Po 9
Xing Ren 9
Pi Pa Ye 9
Bai Bu 9
Lu Gen 15
Ting Li Zi 9
Bai Qian 9
Herbs to Release the Exterior Fang Feng 9
Herbs to Restore Lung Qi dynamic Zhi Ke 9
Jie Geng 6
Gua Lou Pi 20
Herbs to Nourish Lung Qi, and Lung Yin Tai Zi Shen 15
Nan Sha Shen 12
Herbs to Resolve Phlegm Zhe Bei Mu 15
Ban Xia 12
Herbs to Clear Heat and dry damp, plus Ashmi Formula Huang Qin 12
Ku Shen 9
Ling Zhi 15
Gan Cao 6

Final outcome

Fourth catch up

After four days on the stop cough formula, we had a quick catch up to see how he was doing with the stop cough herbs. He said his cough was 90% resolved, with a residual tightening at the end of his outbreath. We agreed to catch up four days later in time to send him follow on herbs, in case we needed to continue treatment.

Fifth and final catch up

After four more days, his cough was completely resolved, and his breathing had returned to normal. We agreed to leave the herbs for the time being, with a caveat that if his breathing worsened at all for 7 days after the herbs had finished, then we would return to herbs to finish the treatment off.

Overall this was clinically a good result, with the main formula having success with his hayfever symptoms, and a reduction in his experience of asthma. This seemed to protect him from experiencing the classic symptoms of itchy nose and eyes, runny nose, sneezing, wheezing, muzzy head and fatigue. It also helped to clear other symptoms of nights sweats and the eczema in his ear.

However, on reflection we could have prepared a formula earlier on to focus more deeply on treating an asthmatic cough, ready to take in case the asthma did become more of a problem, which it had done. There is a principle of treating what we see, and because the asthma symptoms in earlier years seemed to come on after the hayfever symptoms, what had happened here was that the asthma still presented, despite not such a strong presentation of the classic hayfever symptoms.

For the following year, I would recommend that we start treating with a main formula again to protect the Lungs a good eight weeks before he usually gets symptoms, in his case mid-February.

I would also give him the smaller ‘hayfever symptoms’ formula as well in case the classic symptoms present, and three days’ worth of a small generic anti-asthma cough prescription to take in case the asthma started to present, giving us enough time to create a more bespoke formula.

Bibliography

1 – Maciocia, Giovanni. The Foundations of Chinese Medicine. Churchill Livingstone 1989 p95

2 – Maciocia, Giovanni. The Foundations of Chinese Medicine. Churchill Livingstone 1989 p83

3 – Maciocia, Giovanni. The Foundations of Chinese Medicine. Churchill Livingstone 1989 p60

4 – Maciocia, Giovanni. The Foundations of Chinese Medicine. Churchill Livingstone 1989 p77

5 – Maciocia, Giovanni. The Foundations of Chinese Medicine. Churchill Livingstone 1989 p63

6 – NCBI:Journal of Alternative and Complementary Medicine: article provided courtesy of Mary Ann Liebert Accessed 03/05/2021 <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830609/#:~:text=ASHMI%20is%20composed%20of%20three,TCM)%2014%2Dherb%20formula.>

7 – American Dragon 2017, accessed 03/05/2021< https://www.americandragon.com/Herb%20Formulas%20copy/BuFeiTang.html>

8 – American Dragon 2017, accessed 03/05/2021< https://www.americandragon.com/Herb%20Formulas%20copy/SiNiSan.html>

9 – American Dragon 2017, accessed 03/05/2021 <https://www.americandragon.com/Herb%20Formulas%20copy/YuPingFengSan.html>

10 – ITM Online, accessed 03/05/2021 http://www.itmonline.org/arts/jadescreen.htm

11 – https://whitecrane.academy/